Catalog_noAB0697
Product_namePDK4 Antibody
Category抗原抗体
ApplicationsWB, IHC-P, FC
ReactivityH, M
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityPurified His-tagged PDK4 protein(Fragment) was used to produced this monoclonal antibody.
DilutionWB,1:500-1:1000;WB,1:1000;WB, 1:250;
PurificationPurified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
othername[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, PDK4, PDHK4
IsotypeIgG1
BackgroundThis gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
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