Catalog_no | AB0697 |
Product_name | PDK4 Antibody |
Category | 抗原抗体 |
Applications | WB, IHC-P, FC |
Reactivity | H, M |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN |
Specificity | Purified His-tagged PDK4 protein(Fragment) was used to produced this monoclonal antibody. |
Dilution | WB,1:500-1:1000;WB,1:1000;WB, 1:250; |
Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
othername | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, PDK4, PDHK4 |
Isotype | IgG1 |
Background | This gene is a member of the PDK/BCKDK protein kinase
family and encodes a mitochondrial protein with a histidine kinase
domain. This protein is located in the matrix of the mitrochondria
and inhibits the pyruvate dehydrogenase complex by phosphorylating
one of its subunits, thereby contributing to the regulation of
glucose metabolism. Expression of this gene is regulated by
glucocorticoids, retinoic acid and insulin. |
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