Catalog_noAB0718
Product_nameHPRT1 Antibody(Ascites)
Category抗原抗体
ApplicationsWB
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:150-178
SpecificityThis HPRT1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from human HPRT1.
DilutionWB,1:500~1600;
PurificationMouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
othernameHypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase, HPRT1, HPRT
IsotypeIgM
BackgroundThe protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
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