| Catalog_no | AB0724 |
| Product_name | LOX Antibody (Center) |
| Category | 抗原抗体 |
| Applications | WB, IHC-P |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:234-260 |
| Specificity | This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX. |
| Dilution | WB,1:100~500; |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| othername | Protein-lysine 6-oxidase, Lysyl oxidase, LOX |
| Isotype | IgG2b |
| Background | The protein encoded by this gene is an extracellular
copper enzyme that initiates the crosslinking of collagens and
elastin. The enzyme catalyzes oxidative deamination of the
epsilon-amino group in certain lysine and hydroxylysine residues of
collagens and lysine residues of elastin. In addition to
crosslinking extracellular matrix proteins, the encoded protein may
have a role in tumor suppression. Defects in this gene are a cause
of autosomal recessive cutis laxa type I (CL type I). Two
transcript variants encoding different isoforms have been found for
this gene. |
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