Catalog_noAB0740
Product_nameMUTED Antibody (Center)
Category抗原抗体
ApplicationsFC, IF, WB
ReactivityH, M
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:40-68
SpecificityThis MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
DilutionWB,1:1000;WB,1:1000;IHC-P,1:50~100;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameBiogenesis of lysosome-related organelles complex 1 subunit 5, BLOC-1 subunit 5, Protein Muted homolog, BLOC1S5, MUTED
IsotypeRabbit Ig
BackgroundThis gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
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