| Catalog_no | AB0746 |
| Product_name | GALNT4 Antibody (N-term) |
| Category | 抗原抗体 |
| Applications | IHC-P, WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:93-120 |
| Specificity | This GALNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human GALNT4. |
| Dilution | WB,1:1000;FC,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Polypeptide N-acetylgalactosaminyltransferase 4, Polypeptide GalNAc transferase 4, GalNAc-T4, pp-GaNTase 4, Protein-UDP acetylgalactosaminyltransferase 4, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4, GALNT4 |
| Isotype | Rabbit Ig |
| Background | This gene encodes a member of the
UDP-N-acetyl-alpha-D-galactosamine:polypeptide
N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.
GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi
apparatus by catalyzing the transfer of GalNAc to serine and
threonine residues on target proteins. They are characterized by an
N-terminal transmembrane domain, a stem region, a lumenal catalytic
domain containing a GT1 motif and Gal/GalNAc transferase motif, and
a C-terminal ricin/lectin-like domain. GalNAc-Ts have different,
but overlapping, substrate specificities and patterns of
expression. In vitro, the encoded protein can complement other
GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem
repeat and can O-glycosylate the P-selectin glycoprotein ligand-1
molecule. The coding region of this gene is contained within a
single exon. |
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