| Catalog_no | AB0775 |
| Product_name | ALOXE3 Antibody (Center) |
| Category | 抗原抗体 |
| Applications | FC, WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:223-252 |
| Specificity | This ALOXE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human ALOXE3. |
| Dilution | ,1:500;,1:500;WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Hydroperoxide isomerase ALOXE3, Epidermis-type lipoxygenase 3, Epidermal LOX-3, e-LOX-3, eLOX-3, Hydroperoxy icosatetraenoate dehydratase, ALOXE3 |
| Isotype | Rabbit Ig |
| Background | ALOXE3 is a member of the lipoxygenase family, which
are catabolized by arachidonic acid-derived compounds. The encoded
enzyme is a hydroperoxide isomerase that synthesizes a unique type
of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic
acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This
epoxy alcohol can activate the the nuclear receptor peroxisome
proliferator-activated receptor alpha (PPARalpha), which is
implicated in epidermal differentiation. Loss of function of the
enzyme encoded by this gene results in ichthyosis, implicating the
function of this gene in the differentiation of human skin. |
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