| Catalog_no | AB0787 |
| Product_name | CASC4 Antibody (C-term) |
| Category | 抗原抗体 |
| Applications | WB, IHC-P, FC |
| Reactivity | H, M |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:336-365 |
| Specificity | This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4. |
| Dilution | WB,1:1000;FC,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4 |
| Isotype | Rabbit Ig |
| Background | The increased expression level of this gene is associated
with HER-2/neu proto-oncogene overexpression. Amplification and
resulting overexpression of this proto-oncogene are found in
approximately 30% of human breast and 20% of human ovarian cancers.
Further characterization of the product of this gene may yield
insight into the fundamental biology and pathogenetic effects of
HER-2/neu overexpression in human breast and ovarian cancer cells.
Alternatively spliced variants encoding different isoforms have
been identified for this gene. |
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