| Catalog_no | AB0811 |
| Product_name | ACF Antibody (C-term) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:394-423 |
| Specificity | This ACF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human ACF. |
| Dilution | WB,1:1000;IHC-P,1:50~100;FC,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | APOBEC1 complementation factor, APOBEC1-stimulating protein, A1CF, ACF, ASP {ECO:0000312|EMBL:CAB947541} |
| Isotype | Rabbit Ig |
| Background | Mammalian apolipoprotein B mRNA undergoes site-specific C
to U deamination, which is mediated by a multi-component enzyme
complex containing a minimal core composed of APOBEC-1 and a
complementation factor encoded by this gene. The gene product has
three non-identical RNA recognition motifs and belongs to the hnRNP
R family of RNA-binding proteins. It has been proposed that this
complementation factor functions as an RNA-binding subunit and
docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest
that the protein may also be involved in other RNA editing or RNA
processing events. |
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