| Catalog_no | AB0853 |
| Product_name | CFH Antibody (Center) |
| Category | 抗原抗体 |
| Applications | FC, WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:751-780 |
| Specificity | This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH. |
| Dilution | IF,1:25;IF,1:25;WB,1:2000;WB,1:2000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Complement factor H, H factor 1, CFH, HF, HF1, HF2 |
| Isotype | Rabbit Ig |
| Background | This gene is a member of the Regulator of Complement
Activation (RCA) gene cluster and encodes a protein with twenty
short concensus repeat (SCR) domains. This protein is secreted into
the bloodstream and has an essential role in the regulation of
complement activation, restricting this innate defense mechanism to
microbial infections. Mutations in this gene have been associated
with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic
nephropathy. Alternate transcriptional splice variants, encoding
different isoforms, have been characterized. |
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