| Catalog_no | AB0885 |
| Product_name | GAD2 Antibody (Center) |
| Category | 抗原抗体 |
| Applications | FC, WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:109-138 |
| Specificity | This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2. |
| Dilution | WB,1:1000;WB,1:1000;IHC-P,1:50~100;IF,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, GAD2, GAD65 |
| Isotype | Rabbit Ig |
| Background | This gene encodes one of several forms of glutamic acid
decarboxylase, identified as a major autoantigen in
insulin-dependent diabetes. The enzyme encoded is responsible for
catalyzing the production of gamma-aminobutyric acid from
L-glutamic acid. A pathogenic role for this enzyme has been
identified in the human pancreas since it has been identified as an
autoantibody and an autoreactive T cell target in insulin-dependent
diabetes. This gene may also play a role in the stiff man syndrome.
Alternative splicing results in multiple transcript variants that
encode the same protein. |
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