Catalog_noAB0887
Product_nameETFA Antibody (C-term)
Category抗原抗体
ApplicationsWB
ReactivityH, M
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:276-304
SpecificityThis ETFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human ETFA.
DilutionIHC-P,1:50~100;FC,1:10~50;WB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameElectron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF, ETFA
IsotypeRabbit Ig
BackgroundETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
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