Catalog_noAB0933
Product_nameRad9 Antibody (S387)
Category抗原抗体
ApplicationsIHC-P, WB
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:365-391
SpecificityThis Rad9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from human Rad9.
DilutionWB,1:1000;IHC-P,1:10~50;IF,1:10~50;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameCell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A
IsotypeRabbit Ig
BackgroundThis gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.
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