Catalog_no | AB0937 |
Product_name | GUCY2D Antibody (Center) |
Category | 抗原抗体 |
Applications | WB |
Reactivity | H, Rat |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:540-570 |
Specificity | This GUCY2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-570 amino acids from the Central region of human GUCY2D. |
Dilution | FC,1:25;WB,1:2000;WB,1:1000;IHC-P,1:50~100; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Retinal guanylyl cyclase 1, RETGC-1, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC, GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1 |
Isotype | Rabbit Ig |
Background | This gene encodes a retina-specific guanylate cyclase,
which is a member of the membrane guanylyl cyclase family. Like
other membrane guanylyl cyclases, this enzyme has a hydrophobic
amino-terminal signal sequence followed by a large extracellular
domain, a single membrane spanning domain, a kinase homology
domain, and a guanylyl cyclase catalytic domain. In contrast to
other membrane guanylyl cyclases, this enzyme is not activated by
natriuretic peptides. Mutations in this gene result in Leber
congenital amaurosis and cone-rod dystrophy-6 diseases. [provided
by RefSeq]. |
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