| Catalog_no | AB0965 |
| Product_name | STARD6 Antibody (C-term) |
| Category | 抗原抗体 |
| Applications | WB, IHC-P, FC |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:187-215 |
| Specificity | This STARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the C-terminal region of human STARD6. |
| Dilution | WB,1:1000;FC,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | StAR-related lipid transfer protein 6, START domain-containing protein 6, StARD6, STARD6 |
| Isotype | Rabbit Ig |
| Background | Cholesterol homeostasis is regulated, at least in part, by
sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM
184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon
sterol depletion, LXRs are inactive and SREBPs are cleaved, after
which they bind promoter SREs and activate genes involved in
cholesterol biosynthesis and uptake. Sterol transport is mediated
by vesicles or by soluble protein carriers, such as steroidogenic
acute regulatory protein (STAR; MIM 600617). STAR is homologous to
a family of proteins containing a 200- to 210-amino acid
STAR-related lipid transfer (START) domain, including STARD6
(Soccio et al., 2002 [PubMed 12011452]). |
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