| Catalog_no | AB0966 |
| Product_name | WTIP Antibody (C-term) |
| Category | 抗原抗体 |
| Applications | WB, FC |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:243-271 |
| Specificity | This WTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human WTIP. |
| Dilution | WB,1:500;IHC-P,1:10~50;IF,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Wilms tumor protein 1-interacting protein, WT1-interacting protein, WTIP |
| Isotype | Rabbit Ig |
| Background | WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity). |
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