Catalog_no | AB1009 |
Product_name | RASGRP2 Antibody (N-term) |
Category | 抗原抗体 |
Applications | WB |
Reactivity | H |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:7-34 |
Specificity | This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human RASGRP2. |
Dilution | WB,1:1000;WB,1:1000;IHC-P,1:10~50;IF,1:10~50; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | RAS guanyl-releasing protein 2, Calcium and DAG-regulated guanine nucleotide exchange factor I, CalDAG-GEFI, Cdc25-like protein, hCDC25L, F25B33 kinase-like protein, RASGRP2, CDC25L, MCG7 |
Isotype | Rabbit Ig |
Background | The protein encoded by this gene is a brain-enriched
nucleotide exchanged factor that contains an N-terminal GEF domain,
2 tandem repeats of EF-hand calcium-binding motifs, and a
C-terminal diacylglycerol/phorbol ester-binding domain. This
protein can activate small GTPases, including RAS and RAP1/RAS3.
The nucleotide exchange activity of this protein can be stimulated
by calcium and diacylglycerol. Three alternatively spliced
transcript variants encoding the same protein have been found for
this gene. |
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