| Catalog_no | AB1016 |
| Product_name | RPGR Antibody (C-term) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:744-772 |
| Specificity | This RPGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids from the C-terminal region of human RPGR. |
| Dilution | WB,1:1000;WB,1:1000;IHC-P,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3 |
| Isotype | Rabbit Ig |
| Background | This gene encodes a protein with a series of six RCC1-like
domains (RLDs), characteristic of the highly conserved guanine
nucleotide exchange factors. The encoded protein is found in the
Golgi body and interacts with RPGRIP1. This protein localizes to
the outer segment of rod photoreceptors and is essential for their
viability. Mutations in this gene have been associated with
X-linked retinitis pigmentosa (XLRP). Multiple alternatively
spliced transcript variants that encode different isoforms of this
gene have been reported, but the full-length natures of only some
have been determined. |
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