| Catalog_no | AB1027 |
| Product_name | HAX1 Antibody (C-term) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:161-190 |
| Specificity | This HAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the C-terminal region of human HAX1. |
| Dilution | WB,1:1000;IHC-P,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1, HS1-binding protein 1, HSP1BP-1, HAX1, HS1BP1 |
| Isotype | Rabbit Ig |
| Background | The protein encoded by this gene is known to associate
with hematopoietic cell-specific Lyn substrate 1, a substrate of
Src family tyrosine kinases. It also interacts with the product of
the polycystic kidney disease 2 gene, mutations in which are
associated with autosomal-dominant polycystic kidney disease, and
with the F-actin-binding protein, cortactin. It was earlier thought
that this gene product is mainly localized in the mitochondria,
however, recent studies indicate it to be localized in the cell
body. Mutations in this gene result in autosomal recessive severe
congenital neutropenia, also known as Kostmann disease. Two
transcript variants encoding different isoforms have been found for
this gene. |
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