| Catalog_no | AB1052 |
| Product_name | HYAL2 Antibody (Center) |
| Category | 抗原抗体 |
| Applications | WB, IHC-P |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:128-157 |
| Specificity | This HYAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human HYAL2. |
| Dilution | WB,1:1000;IHC-P,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Hyaluronidase-2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2, LuCa-2, HYAL2, LUCA2 |
| Isotype | Rabbit Ig |
| Background | This gene encodes a weak acid-active hyaluronidase. The
encoded protein is similar in structure to other more active
hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major
glycosaminoglycans of the extracellular matrix. Hyaluronan and
fragments of hyaluronan are thought to be involved in cell
proliferation, migration and differentiation. Although it was
previously thought to be a lysosomal hyaluronidase that is active
at a pH below 4, the encoded protein is likely a GPI-anchored cell
surface protein. This hyaluronidase serves as a receptor for the
oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of
several related genes in a region of chromosome 3p21.3 associated
with tumor suppression. This gene encodes two alternatively spliced
transcript variants which differ only in the 5' UTR. |
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