| Catalog_no | AB1053 |
| Product_name | PSTPIP1 Antibody (N-term) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:89-118 |
| Specificity | This PSTPIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human PSTPIP1. |
| Dilution | WB,1:1000;FC,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP, PSTPIP1, CD2BP1 |
| Isotype | Rabbit Ig |
| Background | The protein encoded by this gene binds to the cytoplasmic
tail of CD2, an effector of T cell activation and adhesion,
negatively affecting CD2-triggered T cell activation. The encoded
protein appears to be a scaffold protein and a regulator of the
actin cytoskeleton. It has also been shown to bind ABL1, PTPN18,
WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA
syndrome. |
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