Catalog_no | AB1081 |
Product_name | PLOD3 Antibody (N-term) |
Category | 抗原抗体 |
Applications | WB, IF |
Reactivity | H |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:78-105 |
Specificity | This PLOD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-105 amino acids from the N-terminal region of human PLOD3. |
Dilution | WB,1:1000; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, Lysyl hydroxylase 3, LH3, PLOD3 |
Isotype | Rabbit Ig |
Background | The protein encoded by this gene is a membrane-bound
homodimeric enzyme that is localized to the cisternae of the rough
endoplasmic reticulum. The enzyme (cofactors iron and ascorbate)
catalyzes the hydroxylation of lysyl residues in collagen-like
peptides. The resultant hydroxylysyl groups are attachment sites
for carbohydrates in collagen and thus are critical for the
stability of intermolecular crosslinks. Some patients with
Ehlers-Danlos syndrome type VIB have deficiencies in lysyl
hydroxylase activity. |
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