Catalog_noAB1105
Product_nameIRAK4 Antibody (N-term)
Category抗原抗体
ApplicationsWB
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:25-52
SpecificityThis IRAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human IRAK4.
DilutionWB,1:1000;WB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameInterleukin-1 receptor-associated kinase 4, IRAK-4, Renal carcinoma antigen NY-REN-64, IRAK4
IsotypeRabbit Ig
BackgroundThis gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
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