| Catalog_no | AB1163 |
| Product_name | CHMP2B Antibody (N-term) |
| Category | 抗原抗体 |
| Applications | WB, FC, IHC-P |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:1-30 |
| Specificity | This CHMP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP2B. |
| Dilution | WB,1:1000;IHC-P,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Charged multivesicular body protein 2b, CHMP25, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2, CHMP2B |
| Isotype | Rabbit Ig |
| Background | This gene encodes a component of the heteromeric ESCRT-III
complex (Endosomal Sorting Complex Required for Transport III) that
functions in the recycling or degradation of cell surface
receptors. ESCRT-III functions in the concentration and
invagination of ubiquitinated endosomal cargos into intralumenal
vesicles. The protein encoded by this gene is found as a monomer in
the cytosol or as an oligomer in ESCRT-III complexes on endosomal
membranes. It is expressed in neurons of all major regions of the
brain. Mutations in this gene result in one form of familial
frontotemporal lobar degeneration. |
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