| Catalog_no | AB1226 |
| Product_name | ARHGDIB Antibody (C-term) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:160-188 |
| Specificity | This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB. |
| Dilution | WB,1:1000;IHC-P,1:10~50; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1 |
| Isotype | Rabbit Ig |
| Background | Members of the Rho (or ARH) protein family (see MIM
165390) and other Ras-related small GTP-binding proteins (see MIM
179520) are involved in diverse cellular events, including cell
signaling, proliferation, cytoskeletal organization, and secretion.
The GTP-binding proteins are active only in the GTP-bound state. At
least 3 classes of proteins tightly regulate cycling between the
GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs),
guanine nucleotide-releasing factors (GRFs), and GDP-dissociation
inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate
of GDP dissociation from Ras-like GTPases (summary by Scherle et
al., 1993 [PubMed 8356058]). |
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