| Catalog_no | AB1241 |
| Product_name | HLA-DPB1 Antibody (Center) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:77-105 |
| Specificity | This HLA-DPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the Central region of human HLA-DPB1. |
| Dilution | ,1:500;,1:500;FC,1:25;WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | HLA class II histocompatibility antigen, DP beta 1 chain, HLA class II histocompatibility antigen, DP(W4) beta chain, MHC class II antigen DPB1, HLA-DPB1, HLA-DP1B |
| Isotype | Rabbit Ig |
| Background | HLA-DPB belongs to the HLA class II beta chain paralogues.
This class II molecule is a heterodimer consisting of an alpha
(DPA) and a beta chain (DPB), both anchored in the membrane. It
plays a central role in the immune system by presenting peptides
derived from extracellular proteins. Class II molecules are
expressed in antigen presenting cells (APC: B lymphocytes,
dendritic cells, macrophages). The beta chain is approximately
26-28 kDa and its gene contains 6 exons. Exon one encodes the
leader peptide, exons 2 and 3 encode the two extracellular domains,
exon 4 encodes the transmembrane domain and exon 5 encodes the
cytoplasmic tail. Within the DP molecule both the alpha chain and
the beta chain contain the polymorphisms specifying the peptide
binding specificities, resulting in up to 4 different molecules. |
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