Catalog_no | AB1281 |
Product_name | SOCS6 Antibody (N-term) |
Category | 抗原抗体 |
Applications | WB |
Reactivity | H |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:40-69 |
Specificity | This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6. |
Dilution | WB,1:1000;IHC-P,1:10~50; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Suppressor of cytokine signaling 6, SOCS-6, Cytokine-inducible SH2 protein 4, CIS-4, Suppressor of cytokine signaling 4, SOCS-4, SOCS6, CIS4, SOCS4 |
Isotype | Rabbit Ig |
Background | The protein encoded by this gene contains a SH2 domain and
a CIS homolog domain. The protein thus belongs to the
cytokine-induced STAT inhibitor (CIS), also known as suppressor of
cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI),
protein family. CIS family members are known to be
cytokine-inducible negative regulators of cytokine signaling. The
expression of this gene can be induced by GM-CSF and EPO in
hematopoietic cells. A high expression level of this gene was found
in factor-independent chronic myelogenous leukemia (CML) and
erythroleukemia (HEL) cell lines. |
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