| Catalog_no | AB1303 |
| Product_name | TMC6 Antibody (N-term) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:160-188 |
| Specificity | This TMC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the N-terminal region of human TMC6. |
| Dilution | WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Transmembrane channel-like protein 6, Epidermodysplasia verruciformis protein 1, Protein LAK-4, TMC6, EVER1, EVIN1 |
| Isotype | Rabbit Ig |
| Background | Epidermodysplasia verruciformis (EV) is an autosomal
recessive dermatosis characterized by abnormal susceptibility to
human papillomaviruses (HPVs) and a high rate of progression to
squamous cell carcinoma on sun-exposed skin. EV is caused by
mutations in either of two adjacent genes located on chromosome
17q25.3. Both of these genes encode integral membrane proteins that
localize to the endoplasmic reticulum and are predicted to form
transmembrane channels. This gene encodes a transmembrane
channel-like protein with 10 transmembrane domains and 2 leucine
zipper motifs. |
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