Catalog_noAB1482
Product_nameMouse Cdk9 Antibody (C-term)
Category抗原抗体
ApplicationsWB
ReactivityH, M
Size100μL/50μL
Price2000.00/1100.00
immunogenMOUSE:251-278
SpecificityThis Mouse Cdk9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of mouse Cdk9.
DilutionWB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameCyclin-dependent kinase 9, Cell division protein kinase 9, Cdk9
IsotypeRabbit Ig
BackgroundMember of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity).
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