Catalog_noAB1631
Product_nameKDM6B Antibody (N-term)
Category抗原抗体
ApplicationsWB, IHC-P
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:167-195
SpecificityThis KDM6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-195 amino acids from the N-terminal region of human KDM6B.
DilutionWB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameLysine-specific demethylase 6B, 11411-, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, Lysine demethylase 6B, KDM6B, JMJD3, KIAA0346
IsotypeRabbit Ig
BackgroundHistone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
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