Catalog_noAB1770
Product_nameOSTM1 Antibody (C-term)
Category抗原抗体
ApplicationsWB
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:292-321
SpecificityThis OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
DilutionWB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameOsteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
IsotypeRabbit Ig
BackgroundThis gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
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