Catalog_no | AB1895 |
Product_name | TMED10 Antibody (C-term) |
Category | 抗原抗体 |
Applications | WB, FC |
Reactivity | H |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:156-185 |
Specificity | This TMED10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human TMED10. |
Dilution | WB,1:1000; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Transmembrane emp24 domain-containing protein 10, 21 kDa transmembrane-trafficking protein, S31III125, S31I125, Tmp-21-I, Transmembrane protein Tmp21, p23, p24 family protein delta-1, p24delta1, p24delta, TMED10, TMP21 |
Isotype | Rabbit Ig |
Background | This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. |
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