Catalog_noAB1929
Product_nameTFEC Antibody(Center)
Category抗原抗体
ApplicationsWB, FC, IF
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:179-205
SpecificityThis TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.
DilutionWB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameTranscription factor EC, TFE-C, Class E basic helix-loop-helix protein 34, bHLHe34, Transcription factor EC-like, hTFEC-L, TFEC, BHLHE34, TCFEC, TFECL
IsotypeRabbit Ig
BackgroundTranscriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.
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