Catalog_no | AB1934 |
Product_name | LRRC8A Antibody(C-term) |
Category | 抗原抗体 |
Applications | WB |
Reactivity | H, M |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | HUMAN:782-810 |
Specificity | This LRRC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 782-810 amino acids from the C-terminal region of human LRRC8A. |
Dilution | WB,1:2000; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Volume-regulated anion channel subunit LRRC8A, Leucine-rich repeat-containing protein 8A, Swelling protein 1, LRRC8A, KIAA1437, LRRC8, SWELL1 |
Isotype | Rabbit Ig |
Background | This gene encodes a protein belonging to the leucine-rich
repeat family of proteins, which are involved in diverse biological
processes, including cell adhesion, cellular trafficking, and
hormone-receptor interactions. This family member is a putative
four-pass transmembrane protein that plays a role in B cell
development. Defects in this gene cause autosomal dominant
non-Bruton type agammaglobulinemia, an immunodeficiency disease
resulting from defects in B cell maturation. Multiple alternatively
spliced transcript variants, which encode the same protein, have
been identified for this gene. |
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