| Catalog_no | AB1937 |
| Product_name | RAET1E Antibody(Center) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:150-179 |
| Specificity | This RAET1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the Central region of human RAET1E. |
| Dilution | WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | NKG2D ligand 4, N2DL-4, NKG2DL4, Lymphocyte effector toxicity activation ligand, RAE-1-like transcript 4, RL-4, Retinoic acid early transcript 1E, RAET1E, LETAL, N2DL4, ULBP4 |
| Isotype | Rabbit Ig |
| Background | Members of the RAET1 family, such as RAET1E, are major
histocompatibility complex (MHC) class I-related genes located
within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins
contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and
RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g.,
RAET1I, or ULBP1; MIM 605697) in that they have type I
membrane-spanning sequences at their C termini rather than
glycosylphosphatidylinositol anchor sequences. RAET1E is a ligand
for NKG2D (KLRK1; MIM 611817), which is expressed on the surface of
several types of immune cells and is involved in innate and
adaptive immune responses (summary by Radosavljevic et al. (2002)
[PubMed 11827464] and Cao et al. (2007) [PubMed
17470428]). |
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