| Catalog_no | AB1958 |
| Product_name | DPEP1 Antibody(N-term) |
| Category | 抗原抗体 |
| Applications | WB, FC |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:1-30 |
| Specificity | This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1. |
| Dilution | WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Dipeptidase 1, Dehydropeptidase-I, Microsomal dipeptidase, Renal dipeptidase, hRDP, DPEP1, MDP, RDP |
| Isotype | Rabbit Ig |
| Background | DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that
hydrolyzes a variety of dipeptides and is implicated in renal
metabolism of glutathione and its conjugates, e.g., leukotriene D4
(Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible for
hydrolysis of the beta-lactam ring of antibiotics, such as penem
and carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier,
beta-lactamase enzymes were thought to occur only in bacteria,
where their probable function was in protecting the organisms
against the action of beta-lactam antibiotics. These antibiotics
exhibit selective toxicity against bacteria but virtual inertness
against many eukaryotic cells (Adachi et al., 1990 [PubMed
2303490]). |
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