| Catalog_no | AB2008 |
| Product_name | PDE8B Antibody (Center) |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | M |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:296-324 |
| Specificity | This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B. |
| Dilution | WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, HsPDE8B, Cell proliferation-inducing gene 22 protein, PDE8B |
| Isotype | Rabbit Ig |
| Background | The protein encoded by this gene is a cyclic nucleotide
phosphodiesterase (PDE) that catalyzes the hydrolysis of the second
messenger cAMP. The encoded protein, which does not hydrolyze cGMP,
is resistant to several PDE inhibitors. Defects in this gene are a
cause of autosomal dominant striatal degeneration (ADSD). Several
transcript variants encoding different isoforms have been found for
this gene. |
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