| Catalog_no | AB2016 |
| Product_name | RRM1 Antibody (N-term) |
| Category | 抗原抗体 |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:71-100 |
| Specificity | This RRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human RRM1. |
| Dilution | WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit, RRM1, RR1 |
| Isotype | Rabbit Ig |
| Background | This gene encodes one of two non-identical subunits that
constitute ribonucleoside-diphosphate reductase, an enzyme
essential for the production of deoxyribonucleotides prior to DNA
synthesis in S phase of dividing cells. It is one of several genes
located in the imprinted gene domain of 11p15.5, an important
tumor-suppressor gene region. Alterations in this region have been
associated with the Beckwith-Wiedemann syndrome, Wilms tumor,
rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and
breast cancer. This gene may play a role in malignancies and
disease that involve this region. |
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