| Catalog_no | AB2023 |
| Product_name | Mouse Txnip Antibody (Center) |
| Category | 抗原抗体 |
| Reactivity | M |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | MOUSE:116-145 |
| Specificity | This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip. |
| Dilution | IHC-P,1:100;WB,1:2000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1 |
| Isotype | Rabbit Ig |
| Background | May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. |
| Instructions | 
查看与下载 |
| Share |
|
