Catalog_noAB2041
Product_nameNeurogenin3 Antibody (N-term)
Category抗原抗体
ReactivityH, M
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:40-69
SpecificityThis Neurogenin3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human Neurogenin3.
DilutionWB,1:2000;WB,1:500;IHC-P,1:25;IHC-P,1:25;WB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
othernameNeurogenin-3, NGN-3, Class A basic helix-loop-helix protein 7, bHLHa7, Protein atonal homolog 5, NEUROG3, ATOH5, BHLHA7, NGN3
IsotypeRabbit Ig
BackgroundNeurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4). DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.
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