| Catalog_no | AB2128 |
| Product_name | APRT Antibody (C-term) |
| Category | 抗原抗体 |
| Reactivity | H, Rat |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN:143-170 |
| Specificity | This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-170 amino acids from the C-terminal region of human APRT. |
| Dilution | WB,1:1000;WB,1:1000;IHC-P,1:50~100; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Adenine phosphoribosyltransferase, APRT, APRT |
| Isotype | Rabbit Ig |
| Background | A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. |
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