| Catalog_no | AB2141 |
| Product_name | Phospho-mouse FADD(S191) Antibody |
| Category | 抗原抗体 |
| Reactivity | M |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | MOUSE |
| Specificity | This mouse FADD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S191 of mouse FADD. |
| Dilution | WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphor |
| othername | FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1 |
| Isotype | Rabbit Ig |
| Background | FADD is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
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