Catalog_noAB2385
Product_nameKallikrein 2 (KLK2) Antibody (C-term)
Category抗原抗体
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:166-197
SpecificityThis Kallikrein 2 (KLK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the C-terminal region of human Kallikrein 2 (KLK2).
DilutionWB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameKallikrein-2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2, KLK2
IsotypeRabbit Ig
BackgroundKallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2; encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.
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