Catalog_noAB2530
Product_nameHS2ST1 Antibody (N-term)
Category抗原抗体
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN:16-45
SpecificityThis HS2ST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human HS2ST1.
DilutionWB,1:1000;WB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
othernameHeparan sulfate 2-O-sulfotransferase 1, 2-O-sulfotransferase, 2OST, 282-, HS2ST1, HS2ST, KIAA0448
IsotypeRabbit Ig
BackgroundHeparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Heparan sulfate 2-O-sulfotransferase is a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of the HS2ST1 gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.
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