| Catalog_no | AB2778 |
| Product_name | Mouse TSC1 Antibody (C-term S1138) |
| Category | 抗原抗体 |
| Reactivity | M |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | :1117-1144 |
| Specificity | This Mouse TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1144 amino acids from the C-terminal region of mouse TSC1. |
| Dilution | WB,1:1000; |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| othername | Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243 |
| Isotype | Rabbit Ig |
| Background | In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). |
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