Catalog_noAB2858
Product_nameM Gpr68 Antibody (Center)
Category抗原抗体
ReactivityM
Size100μL/50μL
Price2000.00/1100.00
immunogenMouse:200-225
SpecificityThis Mouse Gpr68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-225 amino acids from the Central region of mouse Gpr68.
DilutionWB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameOvarian cancer G-protein coupled receptor 1, G-protein coupled receptor 68, Sphingosylphosphorylcholine receptor, Gpr68, Ogr1
IsotypeRabbit Ig
BackgroundProton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
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