Catalog_noAB2885
Product_nameDANRE shha Antibody (Center)
Category抗原抗体
ReactivityZf
Size100μL/50μL
Price2000.00/1100.00
immunogenZebrafish
SpecificityThis shha antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 151-162 amino acids from the Central region of DANRE shha.
DilutionWB,1:1000;
PurificationPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
othernameSonic hedgehog protein A, SHHA, VHH-1, Sonic hedgehog protein A N-product, Sonic hedgehog protein A C-product, shha, shh, vhh1
BackgroundIntercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
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