Catalog_no | AB2885 |
Product_name | DANRE shha Antibody (Center) |
Category | 抗原抗体 |
Reactivity | Zf |
Size | 100μL/50μL |
Price | 2000.00/1100.00 |
immunogen | Zebrafish |
Specificity | This shha antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 151-162 amino acids from the Central region of DANRE shha. |
Dilution | WB,1:1000; |
Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
othername | Sonic hedgehog protein A, SHHA, VHH-1, Sonic hedgehog protein A N-product, Sonic hedgehog protein A C-product, shha, shh, vhh1 |
Background | Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity). |
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