Catalog_noAB2916
Product_nameSMARCD3 Antibody (N-term)
Category抗原抗体
ReactivityH
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis SMARCD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-60 amino acids from the N-terminal region of human SMARCD3.
DilutionIF,1:25;WB,1:1000;
othernameSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3, 60 kDa BRG-1/Brm-associated factor subunit C, BRG1-associated factor 60C, BAF60C, SMARCD3, BAF60C
IsotypeRabbit Ig
Background Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Instructions 查看与下载
Share


联系我们
苏州博奥龙科技有限公司(实验室)
苏州博特龙免疫技术有限公司(商务)
地址:苏州工业园区金鸡湖大道99号苏州纳米城西北区14幢203室
          苏州相城经济开发区观塘路1号西交大漕湖科技园C幢810室
电话:400-921-8278
联系人:刘经理
手机:13552826508 / 13552713240
北京博奥龙微信公众号
扫一扫关注我们

Copyright © 2021 苏州博特龙免疫技术有限公司 版权所有 ,苏ICP备2021013855号-1  

佐剂 细胞冻存液 抗体制备 慢病毒包装 免疫检测