| Catalog_no | AB3034 |
| Product_name | NDN Antibody (N-term) |
| Category | 抗原抗体 |
| Reactivity | H |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN |
| Specificity | This NDN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-109 amino acids from the N-terminal region of human NDN. |
| Dilution | WB,1:1000; |
| othername | Necdin, NDN |
| Isotype | Rabbit Ig |
| Background | Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity). |
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