Catalog_noAB3038
Product_name(Mouse) Mlf1 Antibody (Center)
Category抗原抗体
ReactivityH, M
Size100μL/50μL
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis (Mouse) Mlf1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 91-126 amino acids from the Central region of (Mouse) Mlf1.
DilutionWB,1:1000;
othernameMyeloid leukemia factor 1, Hematopoietic lineage switch 7, Myelodysplasia-myeloid leukemia factor 1, Mlf1, Hls7
IsotypeRabbit Ig
Background Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
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