| Catalog_no | AB3064 |
| Product_name | Mouse Hes1 Antibody (Center) |
| Category | 抗原抗体 |
| Reactivity | M |
| Size | 100μL/50μL |
| Price | 2000.00/1100.00 |
| immunogen | HUMAN |
| Specificity | This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of Mouse Hes1. |
| Dilution | WB,1:1000; |
| othername | Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1 |
| Isotype | Rabbit Ig |
| Background | Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity). |
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